The project Chiron is funded by Eurostars, a european programme specifically dedicated to research performing SMEs. Eurostars stimulates them to lead international collaborative research and innovation projects. The programme is market driven, focusses on the needs of SMEs and specifically targets the development of new products, processes and services and the access to transnational and international markets. The aim of the project is to create a smart multimaterial bioprinting platform for the research and production in the biomedical sector to create a portfolio of biomaterials and applications.
Chiron is an international collaboration between two SMEs (Concr3de BV and IPC,Innovative Polymer Compounds) and two research centers (University Medical Center of Utrecht and the Trinity College of Dublin).
The team is composed by top researchers and high tech companies to create solutions for the biomedical sector. The expertise goes from biomaterials and biofabrication to hardware and software development to create taylor made solution for the biomedical industry.
Professor, Tissue Engineering, Trinity College Dublin
Prof. Kelly leads a multidisciplinary musculoskeletal tissue engineering group based in the Trinity Centre for Biomedical Engineering. The goal of his laboratory is to understand how environmental factors regulate the fate of adult stem cells. This research underpins a more translational programme aimed at developing novel tissue engineering and 3D bioprinting strategies to regenerate damaged and diseased musculoskeletal tissues. To date he has published over 180 articles in peer-reviewed journals and secured over €18 million in research funding.
Contacts: kellyd9@tcd.ie
Role in the project: Principle Investigator
Professor, Orthopaedics, UMC Utrecht
Professor Jos Malda is Head of Research at the Department of Orthopaedics, University Medical Center Utrecht and the Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Utrecht. He also leads the Utrecht Biofabrication Facility. He received his MSc degree in Bioprocess Engineering (Wageningen University, 1999) and completed his PhD on Cartilage Tissue Engineering in 2003 (University of Twente). He subsequently accepted a research fellowship at the Institute of Health and Biomedical Innovation, (Queensland University of Technology, Brisbane, Australia). In 2007, Dr. Malda was awarded a fellowship that allowed him to establish his research group in Utrecht. Dr. Malda has published over 175 articles in peer-reviewed international journals, attracted over 10 million Euro in research funding and holds an ERC Consolidator grant. Further, he is one of the initiators of the first international master’s program in Biofabrication. From 2014-2018, he was the president of the International Society for Biofabrication. He is a pioneer in the field of biofabrication and his research aims to promote tissue regeneration by recreating 3D biological environments with the aid of biofabrication technologies. Bioprinted constructs are evaluated in ex vivo defect models and bioreactors to provide tissue maturation and validation as close as possible as that occurring in the in vivo situation. Moreover, promising strategies are translated towards in vivo models with potential impact in human and veterinary medicine.
Contacts: j.malda@umcutrecht.nl
Role in the project: Principle Investigator
Postdoctoral Researcher, UMC Utrecht
Paula Vena is currently a postdoctoral researcher at the Department of Orthopedics, University Medical Center Utrecht (UMC Utrecht) and at the Department of Biomedical Engineering, Eindhoven University of Technology (TU/e). Paula followed her undergraduate studies in Chemical Sciences at the University of Buenos Aires, Argentina. She received her PhD degree in Chemistry from the Eindhoven University of Technology. She was part of the Marie Skłodowska-Curie Innovative Training Network MULTIMAT. She studied the self-assembly of synthetic and natural polymers and the formation of hybrid polymer-silica structures. She used advanced electron microscopy techniques, such as (cryo)-transmission electron microscopy and (cryo)-electron tomography to study the complex nanostructures. Currently, her postdoctoral research focuses on the development and biofabrication of materials for bone tissue engineering.
Contacts: m.p.vena@umcutrecht.nl ; m.p.vena@tue.nl
Role in the project: Postdoctoral Researcher
Assistant Professor, UMC Utrecht
Miguel Castilho is currently an assistant Professor in Biofabrication at the Department of Orthopedics, University Medical Center Utrecht (UMC Utrecht) and at the Department of Biomedical Engineering, Eindhoven University of Technology (TU/e). Miguel holds a MSc degree in Mechanical Engineering and a PhD in Biomedical engineering (with high distinction, 2015) from the Technical University of Lisbon (IST, Portugal). Miguel worked & was a visiting researcher in several research groups across the world: University of Würzburg, (Germany); University of Birmingham (UK); University of Wollongong (AU); University of Lisbon (Portugal); Eindhoven University of Technology (The Netherlands), in the field of biomaterials design and 3D printing. Miguel has published over 45 publications in peer reviewed journals and has secured more than 2 million Euro in competitive national and international grants. His junior research group is focused on the design and processing of biomaterials to build and study living materials. A particular focus lies on engineering mechanical competent implants for bone regeneration using advanced 3D printing technologies.
Contacts: m.diascastilho@umcutrecht.nl; m.dias.castilho@tue.nl
Role in the project: Principle Investigator
Cofounder, Concr3de
Matteo Baldassari is the founder and Co-owner of Concr3de, a company specilized in building additive manufacturing systems and materials. Matteo is involved in both the technical and business development of the company with the goal to grow the company and increase the portfolio of applications and materials.
Matteo is currently focusing on the development of new materials and innovative solutions with a strong focus on Healthcare and medical solutions. Matteo has more then 10 years experience in digital manufacturing and computational design. Matteo secured more then 2M euro in R&D and innovative projects through national and international collaborations.
Matteo is currently leading and coordinating the consortium of CHIRON with the purpose to provide better and smarter solutions to the biomedical and healthcare industry.
Before funding Concr3de, Matteo graduated cum laude from the University of architecture in Rome with a master in Technologies and sustainability. He worked for several engineering firms and research centers with a focus on digital, computational design and robotic manufacturing. Matteo graduated cum laude from the University of architecture in Rome with a master in Technologies and Sustainability.
Contacts: info@chiron-biotech.com
Role in the project: Project Coordinator and Principal investigator
Biomechanical engineer, Concr3de
Ion Martinez de Apellaniz is currently working at Concr3de as an R&D Mechanical Engineer. He completed his BSc in Mechanical Engineering (University of Navarra, 2017), followed by a MSc in Biomechanical Design (TU Delft, 2019). After working as a software consultant, he joined Concr3de in 2020, to be in charge of the design, production and testing of the binder jetting 3D printers developed in the company. With a great interest in the biomedical world, he was also responsible for the development of the ArmadilloBio and Chamaleon printers, involved from the ideation, supply and production, until the testing of the machines. The design process included checking materials compatibility, adaptation to the scale of medical applications and allowing the use of different medical inks and powders.
Contacts: ion@chiron-biotech.com
Role in the project: Principal investigator
R&D Material Engineer at Concr3de
Following his experience as a graduate research fellow at various institutes, where he focused on inkjet printing of ceramics parts and the material and mechanical characteristics of Solid Oxide Fuel Cells, he successfully obtained his Ph.D. in “Materials, Mechatronics, and Systems Engineering” in 2022. His research activities have been primarily centered around the development of the P-3DP (Powder-based binder jetting 3D Printing) technique for the creation of inorganic materials.
At present, he is engaged in the development of new products through the utilization of binder jetting technology.
Contacts: farid@concr3de.com
Role in the project: Principal investigator
Technical Director, IPC – Innovative Polymer Compounds
Joe is extensively qualified in the field of polymer engineering, possessing third level qualifications from the Athlone Institute of Technology and the Sligo Institute of Technology in Polymer and Plastics Engineering. He had over 25 years of industry experience in PVC compounding and formulation, before joining IPC – Innovative Polymer Compounds in 2008 as their Technical Director. Throughout his time in IPC – Innovative Polymer Compounds Joe has formulated and developed compounding procedures for hundreds of medical compounds which are supplied to some of the foremost medical device companies in the world.
Contacts: jmolloy@ipcpolymers.ie
Role in the project: Principal investigator
Director/Co-Owner, IPC – Innovative Polymer Compounds
Henrik is responsible for sales and marketing as well as other management duties at IPC – Innovative Polymer Compounds. He has a BA in Business Administration, specialising in languages and marketing from the European Business School in London (which is now Regent’s University London). He speaks 4 (and ½!) languages and has lived, studied and worked in 7 countries. He has been involved with IPC – Innovative Polymer Compounds since it started and owns 50% of the company.
Contacts: hbjoerk@ipcpolymers.ie
Role in the project: Principal investigator
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The project Chiron is funded by Eurostars, a maket driven european programme dedicated to R&D performing SMEs.